Endocrine Abstracts

Successful pregnancy depends on the ability of the maternal immune system to tolerate a genetically incompatible feto-placental unit. One of the important adaptations leading to this immuno-tolerance is the shift, at implantation, of Th 1 dominance to Th 2 dominance. Successful pregnancy is a Th2 dominant immune state, therefore, it is not surprising that women with a Th 1 dominant immune disease such as rheumatoid arthritis, thyroiditis or multiple sclerosis improve during pr...

Objectives: The insulin-sensitivity regulator adipocyte fatty acid-binding protein 4 (FABP4) integrates metabolic and inflammatory responses. We hypothesize that there is relationship between FABP4 and factors related to metabolic syndrome in pregnancy-induced hypertension (PIH).Materials and methods: In this prospective observational study, among the 72 relatively overweight (BMI≥24 kg/m2) nulliparous women, 14 developed non-proteinuric...